How Long Does Percocet Stay In Your System?

How Long Does Percocet Stay In Your System? Percocet is the most prescribed medicine, which is combined with opioid oxycodone with the analgesic acetaminophen. The acetaminophen is the most active ingredient in Tylenol.

This medication is used for short-term treatment of pain. Percocet is available in the market in tablet form and is used to treat a variety of pains like intestinal pressure, chronic back pain, and gallstone pain.

Its typical dose varies according to conditions, medical history, and severity of pain. It may range from 2.5mg to 10mg. You must know that the Drug Enforcement Administration classified Percocet as a Schedule ll drug, meaning it has a high potential for abuse.

To avoid misuse, several governments have passed different laws on prescribing practices. The opioid component of this drug is responsible for the development of tolerance, and its larger dose is used to achieve desired effects.

This drug is responsible for the development of addiction and other health effects. It is essential to prevent drug addiction; for this, you must know about drug time to stay in the body system. In this article, our main topic of discussion is “How long does Percocet stay in your system?”

Table of Contents

What Is The Basic Purpose Of Percocet?

Percocet is mainly used to treat severe pain. This drug is used when alternative medicines are ineffective in treating pain. These medications include:

  • Paracetamol
  • Analgesics like aspirin
  • Non-medicated techniques such as
  • Cooling
  • Heating
  • Physiotherapy

Percocet is an orally used medicine that is a combination of Oxycodone and acetaminophen. Oxycodone is the most potent painkiller, and it is somehow better than Oxycodone, which is a non-prescribed painkiller.

Note that acetaminophen is also responsible for boosting Oxycodone’s discomfort-managing properties. DEA classified Oxycodone as Schedule II prohibited. It is due to its misuse and addiction possibility. It is also the preferred substance for occupational drug screening.

Lets Explore: How Long Does Xanax Stay In Your System?

How Long Does Percocet Stay In Your System?

How long does Percocet stay in your system? It basically depends on the typical half-life of the drug. Half-life is the time a drug takes to reduce up to half.

You can also determine withdrawal symptoms by using elimination half-life. Oxycodone is considered a short-acting opioid due to its half-life of 3.5 hours.

Note that acetaminophen has a half-life shorter than Oxycodone. Oxycodone is a short-acting and immediate-release drug that lasts up to 3 hours.

The typical effects of Percocet generally last for about 4 to 6 hours, so you should take medicine before 4 to 6 hours.

Also Read: How Long Does Meth Stay In Your System?

Factors Influencing The Half-Life Of Percocet:

There are many factors which are responsible for Percocet to stay in your system:


  • Age influences considerable time to stay off drugs in the system.
  • Adults the age of 40+ will remove Percocet more slowly compared to those under 40 years.

Duration of use:

  •       Percocet may stay longer than usual in the body after sustained use. We conclude that you can detect substances longer after the last dose.

Liver and kidney function:

  • A person with liver and kidney problems will metabolize drugs more slowly than usual.


  • If your body’s metabolism is fast, it will leave quicker than a sick individual.

How Long Does Percocet Stay In Your Urine?

Like other drugs, the Percocet detection urine test is inexpensive and the most commonly used. Percocet typically stays in a person’s urine for about 48 hours. In addition, it typically depends on liver and kidney function.

How Long Does Percocet Stay In Your Hair?

Percocet remains typically present in a person’s hair for about 30 days. This substance is most commonly used, especially in case of detection of substance abuse.

How Long Does Percocet Stay In Your Blood?

You can detect Percocet in a person’s blood for about 24 hours. Furthermore, it has too low a detection period.

How Long Does Percocet Stay In Your Saliva?

Percocet detection time in saliva is longer than in blood and typically stays in saliva for 4 days.

What Is The Half-Life Of Percocet?

Percocet’s half-life varies, and its typical half-life is about 3.5 hours. To remove all the substances from the body system, there is a requirement of about 5 half-lives. In simple words, you need about 19 hours to eliminate completely from the system.

This procedure is mainly present in those using Percocet for a long time.

Related: How Long Does Cocaine Stay In Your System?

What Do You Know About The Risks Of Percocet Abuse?

Besides its detection period in the body system, there are some other adverse effects associated with its abuse that you must know. A person who uses Percocet according to physician instruction will have to face the least negative symptoms.

On the other hand, if a person uses Percocet more than need will have to face more adverse effects than usual. You must know that most physicians try to find alternatives to Percocet due to its dangers and harmful impacts.

If your physician prescribes this medication, you must notice body changes and ask your medical practitioner to prescribe any alternative with fewer adverse effects. There are some negative effects associated with Percocet use, which are given below:

  • Morning illness
  • Dry mouth
  • Migraine
  • Chucking up
  • Tiredness
  • Mood swings

There are also some adverse effects for which you must seek medical assistance:

  • Vomiting
  • Skin infection
  • Difficulty in breathing
  • Loss of management
  • Heartache
  • Dry cough
  • Convulsions
  • Swelling of

Ø Facial

Ø Nasal

Ø Esophagus

Ø Mouth

Ø Lips

Ø Eyelids

Ø Foot

Ø Ankle

What Are The Long-Term Side Effects Of Percocet?

These are some long-term side effects of Percocet:

  • Acetaminophen is present in Percocet and is involved in liver damage.
  • Oxycodone, the central part of Percocet, is involved in kidney damage.
  • Slow breathing is also associated with the use of opioid use.
  • Irregular heartbeat and other CVS problems like high pressure are also associated.
  • It is also responsible for hormonal imbalances resulting in mood swings and irritability.
  • It is also associated with male and female sexual dysfunction.
  • This drug also impairs neurotransmitter functions, which can negatively affect memory, decision-making, and cognition.

Conclusion: How Long Does Percocet Stay In Your System?

Percocet is mainly used to treat severe pain. This drug is used when alternative medicines are ineffective in treating pain. How long does Percocet stay in your system? It basically depends on the typical half-life of the drug. Percocet generally lasts for about 4 to 6 hours in the human body. Convulsions, morning illness, and dry mouth are some risk factors of Percocet use.

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